SEMORELIN

Product Overview

Sermorelin (GRF 1-29) is the shortest synthetic portion of GHRH that retains the full biological potency of the naturally occurring hormone. In laboratory settings, it is a primary tool for studying the hypothalamic-pituitary-somatotropic axis. Research focused on this peptide examines the mechanical triggers for growth hormone release and the subsequent downstream effects on cellular growth and metabolism.

• Receptor Affinity: Studied for its highly specific binding to the GHRH receptors in the anterior pituitary.

• Signaling Models: Investigated for its role in stimulating adenylate cyclase and the cyclic AMP (cAMP) dependent pathway.

• Hormonal Regulation: Used to model the pulsatile release of somatotropic hormones in controlled cellular environments.

Specifications

• Sequence: His-DAla-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2

• Form: Lyophilized powder

• Storage: Store dry at 2°C–8°C. For long-term stability, store at -20°C. After reconstitution, keep refrigerated at 2°C–8°C and use within a specified experimental window.

• Solubility: Soluble in sterile water, bacteriostatic water, or dilute acetic acid.

Research Applications

This peptide is commonly utilized in in vitro studies involving:

• Pituitary Function Models: Examining the kinetics of growth hormone secretion.

• Cell Proliferation: Investigating the effects of GHRH analogs on various tissue cell lines.

• Sleep and Circadian Research: Studying the interface between metabolic hormones and biological rhythms.

• Aging and Senescence: Researching the decline of somatotropic activity in cellular aging models.

Usage Notes

• Bacteriostatic water is sold separately.

• Supplied in a stabilized, lyophilized form to ensure maximum shelf life prior to laboratory use.

Intended Use

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not approved for human or veterinary use and must not be used in food, pharmaceuticals, cosmetics, or diagnostic applications.

Disclaimer & Terms

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. All sales are final. By purchasing, the buyer confirms they are qualified to handle research compounds and assumes full responsibility for proper handling, storage, and compliance with all applicable laws and regulations.